Senescence,Aging,Aging Difficulties


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Senescence



	In biology, senescence is defined as �combination of deterioration processes after the development period of a living organism�. The word senescence originates from the Latin word senex, which means old age or old man. The science of elderly care is gerontology, an important feature of facts about aging.
Cellular senescence is when normal diploid differentiated cells can no longer divide. This phenomenon is known as replicative senescence or Hayflick phenomenon or Hayflick limit. It is named in honor of Dr. Leonard Hay flick who published it in 1965. In response to DNA damage, cells self-destruct or senesce if the damage cannot be repaired. In cellular suicide, the death of one or many cells can be expected to benefit the organism in its entirety. Organismal senescence whole organisms aging. The term aging and senescence are often used in each other's place. Aging is normally characterized by the lessening ability to cope with stress, increased homeostatic imbalance and aging difficulties. As a result death is ultimate aging consequence of aging. Maximum life span differences between species are directly related to different rates of aging. A mouse is thus elderly at 3 years and a human being only at 90 years. The genetic differences affect a variety of physiological processes, including efficiency of DNA repair, rates of free radical production and antioxidant enzymes. The senescence process with aging difficulties is complex. Species don't become immortal and will succumb to trauma or disease. Average lifespans may greatly vary between and within species as both environmental and genetic factors contribute to aging. Programmed theories imply that aging is regulated by biological clocks. Stochastic theories blame environmental impacts on living organisms that induce cumulative damage at various levels as the cause of aging, examples which range from damage to deoxyribonucleic acid (DNA), damage to tissues and cells by oxygen radicals (widely known as free radicals countered by the even more well known antioxidants), and cross-linking. The problems in aging and senescence understanding are many.


Facts About Aging

Senescence	Lifespan of a Human Being
Effects of Aging	Gerontology

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